The IT Center (ITC) is a central facility of RWTH Aachen University, operating HPC equipment and supporting the computational sciences, fundamental for RWTH's strategy. The ITC performs research and methodical support with a focus on Virtual Reality and High Performance Computing, committed to the enhancement of user productivity and application performance. This talk presents the infrastructure and methodical support offerings for simulation science at RWTH. It gives an overview about the application landscape at RWTH and explains how application development is supported by research in programming models and tools.