Students and faculty alike are clearly spending much more of their days interacting with computing and communication tools than with each other. Is this good? Are all uses of technology in education helpful, and if not, how does one separate the benefits from the burdens? We will explore how technology enables dynamic representation in the sciences, arts, and humanities, giving us the opportunity to be more fully human as we seek new knowledge in service to society. Moving “beyond PowerPointless-ness,” we have the opportunity to demonstrate that computing really matters. Computing “matters” because quantitative reasoning, computational thinking, and multiscale modeling are the intellectual “heart and soul” of 21st Century science and therefore are the essential skills of the 21st Century workforce. Computing “matters” because we can apply the power of interactive computing to reach a deeper understanding of math and science and their role in understanding the world.